ncRNA name | mmu-miR-27a |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Mus musculus |
Tissues/Cell_line | UM samples |
Methods | MTT assay, qRT-PCR |
Expression pattern | associated |
Functional description | We for the first time report a correlation between antitumor activity of genistein and miR-27a mediated regulatory mechanism. Genistein markedly inhibited miR-27a expression.The levels of miR-27a and its target gene ZBTB10 were significantly different based on the dose of genistein. |
PubMed ID | 19639204 |
Year | 2009 |
Title | Genistein inhibits growth of human uveal melanoma cells and affects microRNA-27a and target gene expression. |
Drug-related ncRNA | YES (Genistein) |
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